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30th May 2013 @ 14:49

About Template

This page contains additional information for the LabTrove ChemSpider SyntheticPages style reaction template. LabTrove posts which are created using this template will be compatible for submission to ChemSpider SyntheticPages

  • For more specific help about these fields and what to fill them with see the corresponding Help page
  • Fields marked * are mandatory
  • Fields marked # correspond to files - you will need to upload the data file into this LabTrove post, and when uploaded click on the "add link to text" button next to it to insert a link in the appropriate point of the template.

Help about fields in template

*Author roles Allowed values for author roles are:
  • abstracter
  • doer
  • spectrum interpreter
  • conceiver
*Procedure or Transformation

Try to use standard classification words, for example substitution, rearrangement, abstraction, metalation, isomerisation, protection, oxidation, reduction, epoxidation, aziridination, cross-coupling, amination etc. Many users will be looking for general procedures which they can modify or apply to their own system.

e.g. "Addition of 2-litioindole to tributyltin chloride" or "alkylation of zirconium tetrachloride with benzyl Grignard" or "Epoxidation of Styrenes with MCPBA".

*Compound being made

Use names rather than formulae.

e.g. "2-indolylstannane", "Zirconium tetrabenzyl" or "Aromatic epoxides".

If this corresponds to a page made using the ChemSpider compound and associated data template then make the page be a link to that LabTrove page.

*Chemicals used (delimited by semicolons ;)

Compound Name (or formula if more useful), supplier or origin, purity?, method of purification?, concentration? Don't forget solvents and chromatographic media etc.

e.g. TBDMS-Cl, 97% (Sigma-Aldrich)

If any correspond to a ChemSpider compound then they can be links to the corresponding ChemSpider page to avoid any ambiguity in what they are e.g.MeOH.

*Procedure
  • We need more detail than would be expected in a journal article; imagine that you are sending the procedure to an inexperienced chemist. We are happy for you to use an informal style to communicate exactly what you did. SyntheticPages is not a journal.
  • Please don't just paste this section from other sources; we want you to include information which will make the procedure work well.
  • Describe the equipment, if non-standard
  • Consider Safety Issues. (see the Terms & Conditions)
  • The procedure should relate to a specific compound rather than being a generic procedure for a group of compounds. if you have synthesised more than one example then please mention this in the text here and/or submit further procedures.
*Authors Comments
  • Any additional tips or thoughts
  • Are any parts difficult or capricious?
  • If you have improved a published procedure, tell us what you think made the difference.
  • Have you done this reaction on a larger or smaller scale?
  • What is the scope of the reaction, how many examples?
  • Has anyone else you know reproduced the protocol or applied it to a different system?
  • Reliability; does it ever fail? If so, why?
  • e.g.
  • Particular care should be taken when handling {name of reagent}
  • This reaction has been performed with a range of alkenes, in our experience good yields were obtained for electron-rich alkenes, but using certain electron-poor alkenes as substrates (for example, acrylates) we obtained lower yields (40-50%)
  • It is important to use freshly distilled tributyl tin hydride, we observed that there was only a small fall-off in yield (
Lead Reference

Your own or other published work (including thesis) in which this procedure might appear. Remember that you retain the right to publish this procedure elsewhere.

e.g. S. Caddick, K. Aboutayab, K. Jenkins, R. I. West, J. Chem. Soc. Perkin Trans. 1, 1996, 675. DOI: 10.1039/P19960000675

Other References

Your own or other published work (including thesis) in which this procedure might appear. Remember that you retain the right to publish this procedure elsewhere.

Multimedia Content

Please use this section is for multimedia content such as embedded spectra and videos.

e.g. Actual NMR spectra (as images or jdx files for interactive spectra), photographs of apparatus, TLC's or crystals or videos. Please contact the ChemSpider team (ChemSpider-at-rsc.org) for help with this.

*#Scheme Structure and Image file

Please upload a reaction scheme in ChemDraw (cdx) format AND a PNG or GIF image of the same reaction scheme. Please remeber that it should be for a specific compound, so no R groups. If you have an older version of the drawing package and cannot write a PNG or GIF then just upload the reaction scheme file

*Data

Enough information to identify the compound (as opposed to fully characterise it); usually at least a 1H NMR.

e.g. 1H NMR, 13C NMR, mp/bp, and any other relevant data such as optical rotation etc.

Compounds Keywords Allowed values are:
Alkanes esters amino acids
alkenes carbonates peptides
alkynes carbamates nucleosides
aromatics/arenes amines heterocyclic compounds
alcohols amides carbocyclic compounds
ethers sulphides isotopically labelled compounds
aldehydes alkyl/alkenyl/aryl halides organometallics
ketones organo phosphorous inorganic compounds
carboxylic acids carbohydrates and sugars  
Reactions Keywords Allowed values are:
substitution radical hydrogenation
addition enzymatic polymerization
elimination oxidation oxidative addition
nucleophilic reduction reductive elimination
electrophilic amination metathesis
thermal hydroxylation insertion
photochemical transition metal catalysed epoxidation

Fields to be populated automatically or when the deposition widget is activated

  • Group
  • Author 1 (First name, Last name, email, organization, role=abstractor)
  • Abstracted submission, Original ID, Original URL
  • Embargo Date(YYYY-MM-DD)
Linked Posts
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