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20th August 2013 @ 09:02

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Reaction information

*#Reaction file
overallscheme_33.cdx
*Reaction file type CDX
*Procedure See child reaction steps
*Yield (%)  
*Type of Yield  
Reference(s)
PhD Thesis - 16Sep2010_final p16.pdf
PhD Thesis - 16Sep2010_final p124.pdf
Further information Compound 33: 1-(2-(trimethylsilyl)ethylthio)-4-(2-(4-(2-(4-(2-(trimethylsilyl)ethylthio)phenyl)ethynyl)-3-nitrophenyl)ethynyl)benzene

For multistep reactions (or their steps):

Overall reaction? True
For overall reaction - links to child reaction steps

Reaction 30: Protection of thiol with alkylsilane: (2-(4-bromophenylthio)ethyl)trimethylsilane

Reaction 31: Sonogashira Coupling: (2-(trimethylsilyl)ethyl)(4-(2-(trimethylsilyl)ethynyl)phenyl)sulfane

Reaction 32: Deprotection of (2-(Trimethylsilyl)ethyl)(4-(2-(trimethylsilyl)ethynyl)phenyl)sulfane: (2-(4-ethynylphenylthio)ethyl)trimethylsilane

Reaction 33: Bidirectional Sonogashira Coupling: 1-(2-(trimethylsilyl)ethylthio)-4-(2-(4-(2-(4-(2-(trimethylsilyl)ethylthio)phenyl)ethynyl)-3-nitrophenyl)ethynyl)benzene

For step in multistep reaction - link to previous reaction step  
For step in multistep reaction - link to following reaction step  
Attached Files
overallscheme_33.cdx
PhD Thesis - 16Sep2010_final p124.pdf
PhD Thesis - 16Sep2010_final p16.pdf