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30th August 2013 @ 13:59

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Reaction information

*#Reaction file
ReactionScheme.cdx
 
*Reaction file type CDX
*Procedure

3-(Dimethyl-tert-butylsilyloxy)-propane-1-(para-toluene sulfonate) (13.634 g, 40 mmol) and NaI (18.0 g, 120 mmol) were refluxed in acetone (150 mL). Then poured into deionised water (50 mL), the solution was then extracted into ether and washed several times with brine, then dried over MgSO4. The compound was then filtered and concentrated to give the title compound. 

*Yield (%) 85
*Type of Yield Isolated Product Yield 
Reference(s)

M. Yotsu-Yamashita, T. Yasumoto, V. H. Rawal, Heterocycles 1998, 48, 79 

DavidOwenThesis2000pp36,37,94.pdf
206LABBOOK.JPG
Further information

Compound 206: (3-Iodopropoxy)(tert-butyl)dimethylsilane

The title compound was prepared by the method of Yotsu-Yamashita et al 

For multistep reactions (or their steps):

Overall reaction? False 
For overall reaction - links to child reaction steps N/A
For step in multistep reaction - link to previous reaction step Reaction 205
For step in multistep reaction - link to following reaction step N/A
Attached Files
ReactionScheme.gif
ReactionScheme.cdx
DavidOwenThesis2000pp36,37,94.pdf
206LABBOOK.JPG